LSVT BIG References

Data-based articles evaluating the efficacy of the LSVT BIG

LSVT BIG References PDF

**OPEN ACCESS ARTICLES

**Estatico, F., Olivares, A., Comini, L., Paneroni, M., Vitacca, M., Tavolazzi, F., Maffi, G., Forlani, C., & Vezzadini, G. (2025). In-Hospital LSVT BIG Training Versus Structured Rehabilitation Treatment in Parkinson’s Disease: Feasibility and Primary Evaluation on Functional and Respiratory Outcomes. Applied Sciences, 15(19), 10611. https://doi.org/10.3390/app151910611

Doucet, B. M., Blanchard, M., & Franc, I. (2025). Effects of LSVT BIG® on Bradykinesia During Activities of Daily Living. OTJR : occupation, participation and health, 15394492251367275. Advance online publication. https://doi.org/10.1177/15394492251367275

**Babcock R, Dawson N, Dawkins H, Morrell E, Rappleyea E, Rogers H, Beato M. (2025) Amplitude-Based Training in Secondary Parkinsonism and Parkinson Plus Syndrome: A Case Series. Adv Geriatr Med Res. 7(2):e250010 https://doi.org/10.20900/agmr20250010

**Babcock RL, Anderson A, Neely L, Speranza C, Wilkerson C, Tolle J, Salik K, Lazaro R, Beato M. (2025) The Effects of Amplitude-Based Training on Mobility, Functional Leg Strength, and Balance Confidence in Persons with Parkinson’s Disease with and Without Deep Brain Stimulation: A Case Series. Adv Geriatr Med Res. 7(2):e250006. https://doi.org/10.20900/agmr20250006

**Sadaghiani, Z., Tahan, N., Ganjeh, S., Baghban, A. A., Khoshdel, A., & Shoeibi, A. (2025). Evaluating the Impact of Adding Lee Silverman Voice Treatment BIG into Routine Physiotherapy on Both Motor and Nonmotor Functions in Individuals with Parkinson’s Disease. Dubai Medical Journal, 8(1), 12–22. https://doi.org/10.18502/dmj.v8i1.18308

Iwai, M., Sakurai, H., Koyama, S., Takeda, K., Hirakawa, Y., Motoya, I., Kanada Y., Okada Y., Kawamura N, Kawamura M., Tanabe, S. (2024). Influence of Mild Cognitive Impairment on LSVT® BIG Therapy Effectiveness in People with Parkinson’s Disease: A Retrospective Cohort Study. Physical & Occupational Therapy In Geriatrics, 1–17. https://doi.org/10.1080/02703181.2024.2430221

**Botkin, L., & Proffitt, R. (2024). Practitioner perspectives on the implementation of the Lee Silverman Voice Treatment BIG® program. Clinical parkinsonism & related disorders, 11, 100268. https://doi.org/10.1016/j.prdoa.2024.100268

**Clarkin, C. M., Ward-Ritacco, C. L., & Mahler, L. (2024). Exercise-Induced Functional Changes in People with Parkinson’s Disease following External Cueing and Task-Based Intervention. Rehabilitation research and practice, 2024, 6188546. https://doi.org/10.1155/2024/6188546

**Eldemir, S., Eldemir, K., Saygili, F., Ozkul, C., Yilmaz, R., Akbostancı, M. C., & Guclu-Gunduz, A. (2024). The effects of standard and modified LSVT BIG therapy protocols on balance and gait in Parkinson’s disease: A randomized controlled trial. Brain and behavior, 14(3), e3458. https://doi.org/10.1002/brb3.3458

**Kaya Aytutuldu, G., Ersoz Huseyinsinoglu, B., Karagoz Sakalli, N., Sen, A., & Yeldan, I. (2024). LSVT® BIG versus progressive structured mobility training through synchronous telerehabilitation in Parkinson’s disease: A randomized controlled trial. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 45(7), 3163–3172. https://doi.org/10.1007/s10072-024-07322-0

Hirakawa, Y., Takeda, K., Koyama, S., Iwai, M., Motoya, I., Sakurai, H., Kanada, Y., Kawamura, N., Kawamura, M., & Tanabe, S. (2024). Effect of the Lee Silverman Voice Treatment BIG® on motor symptoms in a participant with progressive supranuclear palsy: A case report. Physiotherapy theory and practice, 40(9), 2171–2178. https://doi.org/10.1080/09593985.2023.2225588

Ekmekyapar Fırat, Y., Turgay, T., Soğan, S. S., & Günel Karadeniz, P. (2023). Effects of LSVT-BIG via telerehabilitation on non-motor and motor symptoms and quality of life in Parkinson’s disease. Acta neurologica Belgica, 123(1), 207–214. https://doi.org/10.1007/s13760-022-02104-x

**Matsuno, A., Matsushima, A., Saito, M., Sakurai, K., Kobayashi, K., & Sekijima, Y. (2023). Quantitative assessment of the gait improvement effect of LSVT BIG® using a wearable sensor in patients with Parkinson’s disease. Heliyon, 9(6), e16952. https://doi.org/10.1016/j.heliyon.2023.e16952

**Turgay, T., Ekmekyapar Fırat, Y., Selver Soğan, S., Günel, P. (2022) Impact of LSVT-BIG ® on Functional Mobility, Walking, Dexterity, and Quality of Life in Parkinson’s Disease. Cukurova Medical Journal, 47(4), 1738-45. https://doi.org/10.17826/cumj.1172689

**Choi, Y., & Kim, D. (2022). Effects of Task-Based LSVT-BIG Intervention on Hand Function, Activity of Daily Living, Psychological Function, and Quality of Life in Parkinson’s Disease: A Randomized Control Trial. Occupational therapy international, 2022, 1700306. https://doi.org/10.1155/2022/1700306

Fleming Walsh, S., Balster, C., Chandler, A., Brown, J., Boehler, M., & O’Rear, S. (2022). LSVT BIG® and long-term retention of functional gains in individuals with Parkinson’s disease. Physiotherapy theory and practice, 38(5), 629–636. https://doi.org/10.1080/09593985.2020.1780655

Hirakawa, Y., Takeda, K., Koyama, S., Naoi, Y., Matsushita, T., Nagai, T., Motoya, I., Sakurai, H., Kanada, Y., Kawamura, N., Kawamura, M., & Tanabe, S. (2022). Effect of Lee Silverman Voice Treatment (LSVT)® BIG on motor symptoms in a patient with severe Parkinson’s disease: a case report. Physiotherapy theory and practice, 38(13), 3159–3168. https://doi.org/10.1080/09593985.2021.1938304

Doucet, B. M., Blanchard, M., & Bienvenu, F. (2021). Occupational Performance and Hand Function in People With Parkinson’s Disease After Participation in Lee Silverman Voice Treatment (LSVT) BIG®. The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 75(6), 7506205010. https://doi.org/10.5014/ajot.2021.042101

Henry W, Cline S, Araujo AC, Ayres N, Gabrielson M, Mears C and Thibault R. (2021). Utilizing Telehealth to Deliver LSVT BIG Treatment for Young Onset Parkinson Disease: A Case Report. Phys Ther Rehabil. 8:7. http://dx.doi.org/10.7243/2055-2386-8-7

Hirakawa, Y., Koyama, S., Takeda, K., Iwai, M., Motoya, I., Sakurai, H., Kanada, Y., Kawamura, N., Kawamura, M., & Tanabe, S. (2021). Short-term effect and its retention of LSVT® BIG on QOL improvement: 1-year follow-up in a patient with Parkinson’s disease. NeuroRehabilitation, 49(3), 501–509. https://doi.org/10.3233/NRE-210129

Iwai, M., Koyama, S., Takeda, K., Hirakawa, Y., Motoya, I., Kumazawa, N., Sakurai, H., Kanada, Y., Kawamura, N., Kawamura, M., & Tanabe, S. (2021). Effect of LSVT® BIG on standing balance in a Parkinson’s patient: A case report. Physiotherapy research international : the journal for researchers and clinicians in physical therapy, 26(4), e1921. https://doi.org/10.1002/pri.1921

Proffitt, R., Henderson, W., Stupps, M., Binder, L., Irlmeier, B., & Knapp, E. (2021) Feasibility of the Lee Silverman Voice Treatment – BIG intervention in stroke. OTJR: Occupation, Participation and Health, 41(1), 40-46. https://doi.org/10.1177/1539449220932908

**Schaible, F., Maier, F., Buchwitz, T. M., Schwartz, F., Hoock, M., Schönau, E., Libuda, M., Hordt, A., van Eimeren, T., Timmermann, L., & Eggers, C. (2021). Effects of Lee Silverman Voice Treatment BIG and conventional physiotherapy on non-motor and motor symptoms in Parkinson’s disease: a randomized controlled study comparing three exercise models. Therapeutic advances in neurological disorders, 14, 1756286420986744. https://doi.org/10.1177/1756286420986744

**Chogle, R., Akre, M., Ladgaonkar S., Kumar A. (2020) Effect of Lee Silverman Voice Therapy (LSVT) BIG Exercises on Functional Gait Performance of Parkinson’s Disease Patients. International Journal of Health Sciences and Research, 10(6), 75-83. https://www.ijhsr.org/IJHSR_Vol.10_Issue.6_June2020/12.pdf

**Blanchard, M., Doucet, B., Perilloux, C., Marchetta, T., Price, D., Pattison, A., Bonanni, G., & Amedee, B. (2020). Functional Performance in People with Parkinson’s Disease: LSVT BIG for LIFE®. Journal of Interprofessional Practice and Collaboration, 2(2). Retrieved from https://repository.ulm.edu/cgi/viewcontent.cgi?article=1026&context=ojihp

**Fillmore, S., Cavalier, G., Franke, H., Hajec, M., Thomas, A., & Moriello, G. (2020) Outcomes following LSVT BIG in a person with normal pressure hydrocephalus: A case report. Journal of Neurologic Physical Therapy, 44(3), 220-227. https://doi.org/10.1097/NPT.0000000000000319

Fishel, S. C., Hotchkiss, M. E., & Brown, S. A. (2020). The impact of LSVT BIG therapy on postural control for individuals with Parkinson disease: A case series. Physiotherapy theory and practice, 36(7), 834–843. https://doi.org/10.1080/09593985.2018.1508260

**Flood, M.W., O’Callaghan, B.P.F., Diamond P., Liegey J., Hughes G., Lowery M.M. (2020). Quantitative clinical assessment of motor function during and following LSVT-BIG® therapy. J Neuroeng Rehabil, Jul 13;17(1):92. https://doi.org/10.1186/s12984-020-00729-8

Henderson, W., Boone, A. E., Heady, J., Nettleton, M., Wilhelm, T., & Bliss, J. (2020). Use of Occupation-Based Measures in LSVT BIG Research: A Case Study. OTJR: Occupation, Participation and Health. 40(2), 131-137. https://doi.org/10.1177/1539449219886261

**Peterka, M., Odorfer, T., Schwab, M., Volkmann, J., & Zeller, D. (2020). LSVT-BIG therapy in Parkinson’s disease: physiological evidence for proprioceptive recalibration. BMC neurology, 20(1), 276. https://doi.org/10.1186/s12883-020-01858-2

Hampton, B. A., Tunney, N., & Dubal, D. (2019). Impact of LSVT BIG on functional outcomes in a patient with Parkinson’s disease: a case study. GeriNotes, 26(1), 20–23.

Kleppang, T. T., & Jørgensen, L. (2019). Dynamic balance and gait speed improve in persons with Parkinson´s disease after Lee Silverman Voice Treatment (LSVT)-BIG training: a single subject experimental design study. European Journal of Physiotherapy, 22(2), 86–96. https://doi.org/10.1080/21679169.2018.1551420

Metcalfe, V., Egan, M., & Sauvé-Schenk, K. (2019). LSVT BIG in late stroke rehabilitation: A single-case experimental design study. Canadian journal of occupational therapy. Revue canadienne d’ergotherapie, 86(2), 87–94. https://doi.org/10.1177/0008417419832951

**Chatto, C. A., York, P. T., Slade, C. P., & Hasson, S. M. (2018). Use of a Telehealth System to Enhance a Home Exercise Program for a Person With Parkinson Disease: A Case Report. Journal of neurologic physical therapy : JNPT, 42(1), 22–29. https://doi.org/10.1097/NPT.0000000000000209

**Isaacson, S., O’Brien, A., Lazaro, J. D., Ray, A., & Fluet, G. (2018). The JFK BIG study: The impact of LSVT BIG on dual task walking and mobility in persons with Parkinson’s disease. Journal of Physical Therapy Science, 30(4), 636-641. https://doi.org/10.1589/jpts.30.636

Pascal, M. R., Ehlers, D., & Hindman, R. (2018). The effects of LSVT BIG home exercises and T’ai Chi on balance and gait in an individual with Parkinson’s disease: a case study. Physical Therapy and Rehabilitation, 5(1), 1–4. DOI:10.7243/2055-2386-5-1

Proffitt, R. M., Henderson, W., Scholl, S., & Nettleton, M. (2018). Lee Silverman Voice Treatment BIG^® for a Person With Stroke. The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 72(5), 7205210010p1–7205210010p6. https://doi.org/10.5014/ajot.2018.028217

**Millage, B., Vesey, E., Finkelstein, M., & Anheluk, M. (2017). Effect on gait speed, balance, motor symptom rating, and quality of life in those with stage I Parkinson’s disease utilizing LSVT BIG®. Rehabilitation Research and Practice, 2017. https://doi.org/10.1155/2017/9871070

Sundaran, A., & Velmurugan, G. (2017). Effectiveness of LSVT big exercise to improve balance in mild to moderate stage Parkinsons patients. International Journal of Medical and Exercise Science, 3(3), 300-311. DOI:10.36678/ijmaes.2018.v03i03.001

**Ueno, T., Sasaki, M., Nishijima, H., Funamizu, Y., Kon, T., Haga, R., Arai, A., Suzuki, C., Nunomura, J. I., Baba, M., & Tomiyama, M. (2017). LSVT-BIG Improves UPDRS III Scores at 4 Weeks in Parkinson’s Disease Patients with Wearing Off: A Prospective, Open-Label Study. Parkinson’s disease, 2017, 8130140. https://doi.org/10.1155/2017/8130140

**Walter, K., Pizzichetta, K., Metz, J., DiCarlo, D., Sieban, A., Toscano, M., Atkins, D., Benitez, J., & Babyar, S. (2017). Improved function and geriatric depression scale profile in outpatients with Parkinson’s disease through the participation in Lee Silverman Voice Therapy BIG^® program. Physical Medicine and Rehabilitation Research, 2, 1-6. https://doi.org/10.15761/PMRR.1000152

**Dashtipour, K., Johnson, E., Kani, C., Kani, K., Hadi, E., Ghamsary, M., Pezeshkian, S., & Chen, J. J. (2015). Effect of exercise on motor and nonmotor symptoms of Parkinson’s disease. Parkinson’s disease, 2015, 586378. https://doi.org/10.1155/2015/586378

Ebersbach, G., Grust, U., Ebersbach, A., Wegner, B., Gandor, F., & Kuhn, A. A. (2015). Amplitude-oriented exercise in Parkinson’s disease: A randomized study comparing LSVT-BIG and a short training protocol. Journal of Neural Transmission, 122(2), 253-256. https://doi.org/10.1007/s00702-014-1245-8

**Ebersbach, G., Ebersbach, A., Gandor, F., Wegner, B., Wissel, J., & Kupsch, A. (2014). Impact of physical exercise on reaction time in patients with Parkinson’s disease-Data from the Berlin BIG study. Archives of Physical Medicine and Rehabilitation, 95(5), 996-999. https://doi.org/10.1016/j.apmr.2013.10.020

Janssens, J., Malfroid, K., Nyffeler, T., Bohlhalter, S., & Vanbellingen, T. (2014). Application of LSVT BIG intervention to address gait, balance, bed mobility, and dexterity in people with Parkinson disease: A case series. Physical Therapy, 94(7), 1014-1023. https://doi.org/10.2522/ptj.20130232

Ebersbach, G., Ebersbach, A., Edler, D., Kaufhold, O., Kusch, M., Kupsch, A., & Wissel, J. (2010). Comparing exercise in Parkinson’s disease–The Berlin LSVT® BIG study. Movement Disorders, 25(12), 1902-1908. https://doi.org/10.1002/mds.23212

Farley, B. G., & Koshland, G. F. (2005). Training BIG to move faster: The application of the speed-amplitude relation as a rehabilitation strategy for people with Parkinson’s disease. Experimental Brain Research, 167(3), 462-467. https://doi.org/10.1007/s00221-005-0179-7